“Codon Distribution In DNA”

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2001.(with A. Som, S. Chattopadhyay and J. Chakrabarti) “Codon Distribution In DNA.” Physical Review E, Vol. 63, issue 5, 051908(pp.051908-1- 051908-8). U.S.A.This paper is based on a presumption: triplets in a genetic string behave almost like linguistic structure. The authors of this paper analogically considered genetic string as a body of linguistic structure By virtue of potentiality of occurrence in a certain context, a linguistic unit (like phoneme [In case of codons, all the nucleotides A, G, T, C may be metaphorically considered as smallest units], Morpheme, lexeme [all the triplets/exons are, for the time being metaphorically considered as words], sentence) enters into interdependent syntagmatic relation. Each triplet occurs syntagmatically with each other, e.g., ATG syntagmatically co-occurs with TTT or TGC, i.e., all the 64 triplets have a definite selectional restriction rule and they are subjected to the Projection Principle at the moment of producing innumerable proteins. One may also say that if some triplets are producing same amino acid are said to be in a paradigmatic relationship (one can be substituted by the other). They are metaphorically considered as synonymous. However, there are some crucial questions: in a given syntagm of a genetic string, how the triplets are distributed? Is there any (inter)dependency relationship among triplets? Before going to answer such crucial questions and before going to deploy Chomskian syntactic tool, we had set our primary task to find out the rank-frequency distribution of triplets. We had deployed a particular Statistico-Linguistic Law, i.e., Zipf’s Law, to understand the rank versus frequency distribution of the codons. What we had found was that the Zipf’s exponent differentiates in case of genetic sequences. http://linguistlist.org/pubs/papers/browse-papers-action.cfm?PaperID=7741 http://arxiv.org/abs/physics/0102021 http://prola.aps.org/abstract/PRE/v63/i5/e051908 http://isid.academia.edu/DebaprasadBandyopadhyay/Papers/388910/_Codon_Distribution_In_DNA._ http://www.researchgate.net/publication/220021081_Codon_Distribution_In_DNA_A._Som_S._Chattopadhyay_J._Chakrabarti__Debaprasad_Bandyopadhyay

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