12. Calandriello R, Tomatis M. Immediate function of single implants using Brånemark System. Prospective one year report of final restorations. - PDF

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TiUnite TiUnite is a highly crystalline and phosphate enriched titanium oxide characterized by a microstructured surface with open pores in the low micrometer range 1. The TiUnite implant surface has repeatedly

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TiUnite TiUnite is a highly crystalline and phosphate enriched titanium oxide characterized by a microstructured surface with open pores in the low micrometer range 1. The TiUnite implant surface has repeatedly proven to give an enhanced bone response compared to machined implant surfaces 2-9. Nobel Biocare has received FDA clearance to claim a more rapid bone formation and greater amount of bone in contact with the TiUnite surface during healing. The enhanced bone response to TiUnite results in faster and stronger osseointegration and, thereby, better maintenance of the implant stability compared to machined titanium implants. When placed in soft bone and immediately loaded, the enhanced osseointegration of Nobel Biocare TiUnite implants results in higher success rates compared to machined implants. These claims are supported by extensive research 2, In addition to the publications supporting the FDA-cleared claims for the TiUnite implant surface, more than fifty references are available, which cover the use of TiUnite implants in various clinical and preclinical situations, using different types of protocols, and with various follow-up times References 1. Hall J, Lausmaa J. Properties of a new porous oxide surface on titanium implants. Appl Osseointegration Res 2000;1: Albrektsson T, Johansson C, Lundgren AK, Sul Y, Gottlow J. Experimental studies on oxidized implants. A histomorphometrical and biomechanical analysis. Appl Osseointegration Res 2000;1: Degidi M, Petrone G Iezzi G, Piatelli A. Histologic evalaution of a human immediately loaded titanium implant with a porous anodized surface. Clin Implant Dent Relat Res 2002;4: Huang YH, Xiropaidis AV, Sorensen RG, Albandar JM, Hall J, Wikesjö UME. Bone formation at titanium porous oxide (TiUnite) oral implants in type IV bone. Clin Oral Impl Res 2005;16: Ivanoff C-J, Widmark G, Johansson C, Wennerberg A. Histologic evaluation of bone response to oxidized and turned titanium micro-implants in human jawbone. Int J Oral Maxillofac Implants 2003;3: Rocci A, Martignoni M, Burgos P, Gottlow J, Sennerby L. Histology of retrieved immediately and early loaded oxidized implants. Light microscopic observations after 5 to 9 months of loading in the posterior mandible of 5 cases. Clin Implant Dent Relat Res 2003;12 ( Suppl 1): Salata LA, Burgos PM, Rasmusson L, Novaes AB, Papalexiou V, Dahlin C, Sennerby L. Osseointegration of oxidized and turned implants in circumferential bone defects with and without adjunctive therapies: an experimental study on BMP-2 and autogenous bone graft in the dog mandible. Int J Oral Maxillofac Surg. 2007;36(1): Schüpbach P, Glauser R, Rocci A, Martignoni M, Sennerby L, Lundgren AK, Gottlow J. The human bone-oxidized titanium implant interface: a microscopic, scanning electron microscopic, back-scatter electron microscopic, and energy-dispersive X-ray study of clinically retrieved implants. Clin Implant Dent Relat Res 2005;7 ( Suppl 1): Zechner W, Tangl S, Furst G, Tepper G, Thams U, Mailath G, Watzek G. Osseous healing characteristics of three different implant types. A histologic and histomorphometric study in mini-pigs. Clin Oral Implants Res 2003;14: Balshi SF, Wolfinger GJ, Balshi TJ. A prospective study of immediate functional loading following the Teeth in a Day protocol: a case series of 55 consecutive edentulous maxillas. Clin Implant Relat Res 2005;7: Brechter M, Nilson H, Lundgren S. Oxidized titanium implants in reconstructive jaw surgery. Clin Implant Dent Relat Res 2005;7 ( Suppl 1):83-87. 12. Calandriello R, Tomatis M. Immediate function of single implants using Brånemark System. Prospective one year report of final restorations. Appl Osseointegration Res 2004;4: Calandriello R, Tomatis M. Simplified treatment of the atrophic posterior maxilla via immediate/early function and tilted implants: a prospective 1-year clinical study. Clin Implant Dent RelatRes 2005;7 ( Suppl 1): Calandriello R, Tomatis M, Vallone R, Rangert B, Gottlow J. Immediate occlusal loading of single molars using Brånemark System Wide Platform TiUnite implants: An interim report of a prospective, open-ended clinical multicenter study. Clin Implant Relat Res 2003;5 ( Suppl 1): Chiapasco M, Gatti C. Immediate loading of dental implants placed in revascularized fibula free flaps: a clinical report on 2 consecutive patients. Int J Oral Maxillofac Implants 2004;19; da Cunha HA, Francischone CE, Filho HN, de Oliveira RC. A comparison between cutting torque and resonance frequency in the assessment of primary stability and final toque capacity of standard and TiUnite single-tooth implants under immediate load. Int J Oral Maxillofac Implants 2004;19: Glauser R, Portmann M, Ruhstaller P, Lundgren AK, Hämmerle C, Gottlow J. Stability measurements of immediately loaded machined and oxidized implants in the posterior maxilla. A comparative clinical study using resonance frequency analysis. Appl Osseontegration Res 2001;2: Glauser R, Ruhstaller P, Windisch S, Zembic A, Lundgren AK, Gottlow J, Hämmerle CHF. Immediate occlusal loading of Brånemark System TiUnite implants placed in predominanatly soft bone: 4-year results of a prospective clinical study. Clin Implant Dent Relat Res 2005;7 ( Suppl1): Glauser R, Zembic A, Ruhstaller P, Windisch S. Five-year results of implants with an oxidized surface placed predominantly in soft quality bone and subjected to immediate occlusal loading. J Prosthet Dent. 2007;97(suppl):S59-S Henry P, Tan A, Allan B, Hall J, Johansson C. Removal toque comparison of TiUnite and turned implants in the Greyhound dog mandible. Appl Osseointegration Res 2000;1: Maló P, Rangert B, Nobre M. All-on-4 immediate-function concept with Brånemark System implants for completely edentulous maxillae: a 1-year retrospective clinical study. Clin Implant Relat Res 2005;7 ( Suppl 1): Olsson M, Urde G, Andersen JB, Sennerby L. Early loading of maxillary fixed cross-arch dental prostheses suppoted by six or eight oxidized titanium implants: Results after 1 year of loading, case series. Clin Implant Relat Res 2003;5 ( Suppl 1): Renouard F, Nisand D. Short implants in severely resorbed maxilla: a 2-year retrospective clinical study. Clin Implant Relat Res 2005;7 ( Suppl 1): Rocci A, Martignoni M, Gottlow J. Immediate loading of Brånemark System with TiUnite and machined surfaces in the posterior mandible. A randomised, open-ended trial. Clin Implant Dent Relat Res 2003;12 ( Suppl 1): Rompen E, DaSilva D, Lundgren AK, Gottlow J, Sennerby L. Stability measurements of a double-threaded titanium implant design with turned or oxidized surfaces. An experimental resonance frequency analysis study in the dog mandible. Appl Osseointegration Res 2000;1: Salata LA, Rasmusson L, Novaes AB, Papalexiou V, Sennerby L. The influence of anodic oxidation on implant integration and stability in bone defects. An RFA study in the dog mandible. Appl Osseointegration Res 2002;3: Vanden Bogaerde L, Pedretti G, Dellacasa P, Mozzati M, Rangert B. Early function of splinted implants in the maxillae and posterior mandibles using Brånemark System TiUnite implants: An 18-month prospective clinical multicenter study. Clin Implant Dent Relat Res 2003;5 ( Suppl 1): Vanden Bogaerde L, Rangert B, Wendelhag I. Immediate/early function of Brånemark System TiUnite implants in fresh extraction sockets in the maxillae and posterior mandibles: an 18-month prospective clinical study. Clin Implant Relat Res 2005;7 ( Suppl 1): van Steenberghe D, Glauser R, Blombäck U, Andersson M, Schutyser F, Pettersson A, Wendelhag I. A computed tomographic scan-derived customized surgical template and fixed prosthesis for flapless surgery and immediate loading of implants in fully edentulous maxillae: a prospective multicenter study. Clin Implant Dent Relat Res 2005;7 ( Suppl 1): Villa R, Rangert B. Early loading of interforaminal implants immediately installed after extraction of teeth presenting endodontic and periodontal lesions. Clin Implant Relat Res 2005;7 ( Suppl 1): Östman PO, Hellman M, Sennerby L. Direct implant loading in the edentulous maxilla using a bone densityadapted surgical protocol and primary implant stability criteria for inclusion. Clin Implant Dent Relat Res 2005;7 ( Suppl 1):60-69. 32. Aalam A-A, Nowzari H. Clinical evaluation of dental implants with surfaces roughened by anodic oxidation, dual acid-etched implants, and machined implants. Int J Oral Maxillofac Implants 2005;20: Achilli A, Tura F, Euwe E. Immediate/early function with tapered implants supporting maxillary and mandibular posterior fixed partial dentures: Preliminary results of a prospective multicenter study. J Prosthet Dent. 2007;97(suppl):S52-S Alsaadi G, Quirynen M, van Steenberghe D. The importance of implant surface characteristics in the replacement of failed implants. Int J Oral Maxillofac Implants 2006;21: Attard N J, David LA, Zarb GA. Immediate loading of TiUnite implants with mandibular overdentures: One-year clinical results of a prospective study. Int J Prosthodont 2005;18: Awillo K, Majewski P, Dijakiewicz M. Immediate loading of one-piece implants - Preliminary studies. EAO Clin Oral Impl Res 2004;15 (4): lii: abstract Balshi SF, Wolfinger GJ, Balshi TJ. Analysis of 164 titanium oxide-surface implants in completely edentulous arches for fixed prosthesis anchorage using the ptergomaxillary region. Int J Oral Maxollofac Implants 2005;20: Becker W, Goldstein M, Becker BE, Sennerby L. Minimally invasive flapless implant surgery: a prospective multicenter study. Clin Implant Dent Relat Res 2005; 7 (Suppl 1): Bedrossian E, Rangert B, Stumpel L, Indresano T. Immediate function with the zygomatic implant: a graftless solution for the patient with mild to advanced atrophy of the maxilla. Int J Oral Maxillofac Implants Nov- Dec;21(6): Brochu J-F, Anderson JD, Zarb GA. The influence of early loading on bony crest height and stability: A pilot study. Int J Prosthodont 2005;18: Buch RSR, Biner J, Wegener J, Wagner W, Reichert T. Drei Jahre klinische Erfarung mit der TiUnite-Oberfläche. Z Zahnärztl Impl 2005;21(4) Chaussé L. Immediate loading of mandibular short implants: 24 cases at 42 months. EAO Clin Oral Impl Res 2004;15(4):lii:abstract Degidi M, Perrotti V, Piattelli A. Immediately loaded titanium implants with a porous anodized surface with at least 36 months of follow-up. Clin Implant Dent Relat Res 2006;8: Duyck J, Vrielink L, Lambrichts I, Abe Y, Schepers S, Politis C, Naert I. Bone response around immediately versus delayed loaded oral implants with ill-fitting prostheses. EAO Clin Oral Impl Res 2004;15(4):lii:abstract Finne K, Rompen E, Toljanic J. Clinical evaluation of a prospective multicenter study on 1-piece implants. Part 1: marginal bone level evaluation after 1 year of follow-up. Int J Oral Maxillofac implants 2007;22(2): Finne K, Rompen E, Toljanic J. Prospective multicenter study of marginal bone level and soft tissue health of a onepiece implant after two years. J Prosthet Dent. 2007;97(suppl):S79-S Friberg B, Dahlin C, Widmark G, Östman PO, Billström C. One-year results of a prospecitve multicenter study on Brånemark System implants with a TiUnite surface. Clin Implant Dent Relat Res 2005; 7 (Suppl 1): Froberg KK, Lindh C, Ericsson I. Immediate Loading of Branemark System Implants: A Comparison Between TiUnite and Turned Implants Placed in the Anterior Mandible. Clin Implant Dent Relat Res 2006;8: Glauser R, Schüpbach, Lundgren AK, Gottlow J, Hämmerle CHF. Machined and oxidized microimplants retrieved from humans: a comparison using histomorphometry and micro-computed tomography. EAO Abstract 64. Clinical Oral Implants Research 2002;13:xxv. 50. Glauser R, Schüpbach P, Gottlow J, Hämmerle CHF. Periimplant soft tissue barrier at experimental one-piece miniimplants with different surface topography in humans: a light-microscopic overview and histometric analysis. Clin Implant Dent Relat Res 2005; 7 (Suppl 1): Gottlow J, Henry P, Tan A, Allan B, Johansson C, Hall J. Biomechanical and histologic evaluation of the TiUnite and Osseotite implant surfaces in dogs. Appl Osseointegration Res 2000;1: Gottlow J, Johansson C, Albrektsson T, Lundgren AK. Biomechanical and histologic evaluation of the TiUnite and Osseotite implant surfaces in rabbits after 6 weeks of healing. Appl Osseointegration Res 2000;1: Hahn J. Clinical and radiographic evaluation of one-piece implants used for immediate function. Accepted for publication in Journal of Oral Implantology (vol 33 issue mid-june). 54. Hahn J. Clinical evaluation of one-piece implants used for immediate function. European J Dent Implantol 2006;2:1 suppl 55. Hall J, Miranda-Burgos P, Sennerby L. Stimulation of directed bone growth at oxidized implants by macroscopic grooves: an in vivo study. Clin Implant Dent Relat Res 2005; 7 (Suppl 1): Jungner M, Lundqvist P, Lundgren S. Oxidized titanium implants (Nobel Biocare TiUnite) compared with turned titanium implants (Nobel Biocare mark III) with respect to implant failure in a group of consecutive patients treated with early functional loading and two-stage protocol. Clin Oral Implants Res 2005;16: Kan JYK, Rungcharassaeng K, Liddelow G, Henry P, Goodacre CJ. Periimplant tissue response following immediate provisional restoration of scalloped implants in the esthetic zone: A one-year pilot prospective multi-center study. J Prosthet Dent. 2007;97(suppl):S109-S Knobloch L, Larsen PA, Rashid B, Carr AB Six-month performance of implants with oxidized and machined surfaces restored at 2, 4, and 6 weeks postimplantation in adult beagle dogs. Int J Oral Maxillofac Implants 2004;19: Kyungsoo H, Sungam C, SangHwan K. Comparison of removal torques between anodizing implant and laser treated implant inserted in the rabbit femoral metaphysis. AO 2004 Poster # Liddelow G, Henry PJ. A prospective study of immediately loaded single implant-retained mandibular overdentures: Preliminary one-year results. J Prosthet Dent. 2007;97(suppl):S126-S Malo P, de Araujo Nobre M, Petersson U, Wigren S. A pilot study of complete edentulous rehabilitation with immediate function using a new implant design: case series. Clin Implant Dent Relat Res. 2006;8(4): Malo P, de Araujo Nobre M, Rangert B. Implants placed in immediate function in peridontally compromised sites: A five-year retrospective and a one-year prospective study. J Prosthet Dent. 2007;97(suppl):S86-S Molly L, Quirynen M, van Steenberghe D. Influence of implant geometry and surface characteristics on primary stability and osseointegration. EAO Clin Oral Impl Res 2004;15(4):lii:abstract Östman PO, Hellman M, Wendelhag I, Sennerby L. Resonance frequency analysis measurements of implants at placement surgery. Int J Prosthodont 2006;19: Palma VC, Magro-Filho O, de Oliveria JA, Lundgren S, Salata LA, Sennerby L. Bone reformation and implant integration following maxillary sinus membrane elevation: an experimental study in primates. Clin Implant Dent Relat Res. 2006;8(1): Portmann M, Glauser R. Report of a case receiving full-arch rehabilitation in both jaws using immediate implant loading protocols: a 1-year resonance frequency analysis follow-up. Clin Implant Dent Relat Res 2006;8: Rao W, Benzi R. Single mandibular first molar implants with flapless guided surgery and immediate function: Preliminary clinical and radiographic study. J Prosthet Dent 2007;97(suppl):S3-S Rocci A, Gottlow J. Esthetic outcome of immediately loaded scalloped implants placed in extraction sites using flapless surgery. A 6 month report of 4 cases. Appl Osseointegration Res 2004;4: Schincaglia GP, Marzola R, Scapoli C, Scotti R. Immediate Loading of Dental Implants Supporting Fixed Partial Dentures in the Posterior Mandible: A Randomized Controlled Split-Mouth Study: Machined Versus Titanium Oxide Implant Surface. Int J Oral Maxillofac implants 2007;22: Schüpbach P, Glauser R, Guggenheim B. Evaluation of in situ biofilms on machined, acid-etched and oxidized titanium surfaces. EAO Clin Oral Impl Res 2004;15(4):li:abstract Schüpbach P, Glauser R, Lundgren AK, Gottlow J, Hämmerle CHF. Evaluation of the bone tissue around implants by a new microtomographic technique. IADR Abstract. J Dent Res 2002; Sennerby L, Miyamoto I. Insertion torque and RFA analysis of TiUnite and SLA implants. A study in rabbit. Appl Osseointegration Res 2000;1: Siepenkothen T, Clauder A, Mehlau R. Multiple center clinical and radiographic evaluation of one-piece implants. European J Dent Implantol 2006;2:1 suppl 74. Siepenkothen T. Clinical performance and radiographic evaluation of a novel single-piece implant in a private practice over a mean of seventeen months. J Prosthet Dent. 2007;97(suppl):S69-S Stephan G, Vidot F, Noharet R, Mariani P. Implant-retained mandibular overdentures: A comparative pilot study of immediate loading versus delayed loading after two years. J Prosthet Dent. 2007;97(suppl):S138-S Suketa N, Sawase T, Tanaka Y, Kjellin P, Wennerberg A, Albrektsson T, Atsuta M. Photocatalytic reaction on TiUnite surfaces. EAO Clin Oral Impl Res 2004;15(4):lii:abstract Turkyilmaz, I. A 3-year prospective clinical and radiologic analysis of early loaded maxillary dental implants supporting single-tooth crowns. Int J Prosthodont, 2006; 19(4): 78. Turkyilmaz I, Sennerby L, Tumer C, Yenigul M, Avci M. Stability and marginal bone level measurements of unsplinted implants used for mandibular overdentures: a 1-year randomized prospective clinical study comparing early and conventional loading protocols. Clin Oral Implants Res 2006;17: Tomatis M, Calandriello R, Rangert B. Immediate loading of Brånemark implants with two different surfaces. EAO Abstract 78. Clinical Oral Implants Research 2002;13(4):abstract Villa R, Rangert B. Immediate and early function of implants placed in extraction sockets of maxillary infected teeth: A pilot study. J Prosthet Dent. 2007;97(suppl):S96-S Wöhrle P.S, Jovanovic SA A biological approach to predictable natural implant esthetics. Appl Osseointegration Res 2004;4: Xiropaidis AV, Qahash M, Lim WH, Shanaman RH, Rohrer MD, Wikesjo UM et al. Bone-implant contact at calcium phosphate-coated and porous titanium oxide (TiUnite)-modified oral implants. Clin Oral Implants Res 2005;16: Yildirim M. Die Bedeutung der Oberflächentopographie in der zahnärztlichen Implantologie. Z Zahnärztl Implantol 2001;56:D Zechner W, Tangl S, Tepper G, Furst G, Bernhart T, Haas R, Mailath G, Watzek G. Influence of platelet-rich plasma on osseous healing of dental implants: A histologic and histomorphometric study in minipigs. Int J Oral Maxillofac implants 2003;18:15-22.
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